A widely cited U.S. survey of LGBTQ youth found that 82% of transgender and non-binary respondents reported depressive symptoms and 54% reported serious suicidal thoughts in the previous year. The study used a self-selected sample and measured self-reported symptoms and thoughts; it does not reflect the number of deaths by suicide.

A large U.S. survey among LGBQ young people found that trans and non-binary participants reported very high rates of depressive mood (82%) and serious suicidal thoughts (54%) in the past year. These figures come from self-reported survey data recruited through LGBTQ advocacy networks.

A 2024 Finnish study by Ruuska et al. found that adolescents referred to gender identity clinics had higher rates of overall mortality and suicide than matched controls. However, after taking previous psychiatric treatment into account, these differences were no longer statistically significant. The findings suggest that pre-existing mental health difficulties, rather than gender dysphoria itself, are the primary predictors of both overall and suicide-related mortality among adolescents seeking gender-related care.

Before accounting for psychiatric history, adolescents referred to gender services had higher rates of all-cause mortality (0.81 versus 0.40 deaths per 1,000 person-years) and suicide mortality (0.51 versus 0.12 deaths per 1,000 person-years). After adjustment for psychiatric treatment history, the hazard ratio for all-cause mortality was 1.0 and the hazard ratio for suicide mortality was 1.8, and neither difference was statistically significant.

^{Price-Feeney, M., Green, A. E., & Dorison, S. H. (2020). Understanding the mental health of transgender and nonbinary youth. Journal of Adolescent Health, 66(6), 684-690. https://doi.org/10.1016/j.jadohealth.2019.11.314}

^{Ruuska, S. M., Tuisku, K., Holttinen, T., & Kaltiala, R. (2024). All-cause and suicide mortalities among adolescents and young adults who contacted specialised gender identity services in Finland in 1996–2019: a register study. BMJ Ment Health, 27(1). https://doi.org/10.1136/bmjment-2023-300940}