Category: Iatrogenic harm

• Puberty blockers disrupt the normal timing of puberty relative to same-age peers, with associated psychosocial effects

  A 2024 systematic review noted that puberty blockers disrupt the normal timing of pubertal development relative to same-age peers. Puberty is an important developmental phase associated with identity formation, body image, emotional development, and peer integration.

  Broader adolescent research has associated variations in pubertal timing with psychosocial outcomes including mood difficulties, social challenges, and depressive symptoms.

  ^{Zepf, F.D. et al. (2024). Beyond NICE: Aktualisierte systematische Übersicht zur Evidenzlage der Pubertätsblockade und Hormongabe bei Minderjährigen mit Geschlechtsdysphorie. Zeitschrift für Kinder- und Jugendpsychiatrie und Psychotherapie, 1-21. DOI: 10.1024/1422-4917/a000972
  PDF: Full paper PDF}

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  • Iatrogenic harm
  • Puberty blockers